|
KMID : 1023920110130010121
|
|
Journal of the Korean Academy of Kinesiology
2011 Volume.13 No. 1 p.121 ~ p.130
|
|
|
The Relationships between Exercise-mediated Fitness and Body Composition with Immune Response to Influenza Vaccine in Elderly Women
|
|
Kim Ki-Jin
|
|
|
Abstract
|
|
|
[INTRODUCTION] The purpose of this study was to examine whether cardiovascular fitness was associated with immune responsiveness of T-lymphocyte to influenza vaccine after regular aerobic exercise in older women.
[METHOD] Exercise group performed 12 week of recreational dance after influenza vaccine, but control group did not perform exercise program. Subjects were measured body composition, VO2max of graded treadmill testing, blood concentration of IgG1, IgG2, Il-10 and IFN-r concentration of ELISA at pre, mid and post-exercise. The relationship
of change of cardiovascular fitness with immune responsiveness of T-lymphocyte to influenza vaccine after regular aerobic exercise program was analyzed by Pearson’s corelation coefficients.
[RESULT] Body composition, blood concentration of IFN-γ and IL-6 showed no significant difference after 12 week exercise program in both groups. Exercise group showed the increased tendency of blood concentration of IgG1 and IgG2 after exercise program. Exercise group showed a significant increase of VO2max after exercise program. This increase of VO2max showed a significant correlations with the activation of blood IgG1 concentration.
[CONCLUSION] This study confirmed that the improvement of cardiovascular fitness was associated with cell-mediated immune responsiveness of T-lymphocyte to influenza vaccine after regular aerobic exercise in older women.
|
|
|
KEYWORD
|
|
|
Immune function, Older women, Exercise, Cardiovascular fitness, Lymphocyte
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|